H79Y (p.His79Tyr) variant of MLH3 (DNA mismatch repair protein Mlh3)
H79Y (p.His79Tyr) in MLH3 (DNA mismatch repair protein Mlh3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
H79Y (p.His79Tyr) variant details
- p.His79Tyr
- ExAC rs754850331
- gnomAD rs754850331
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.20
- CADD 8.25
- PolyPhen-2 0.03
- SIFT 0.08
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available