C25* (p.Cys25Ter) variant of MLH3 (DNA mismatch repair protein Mlh3)
C25* (p.Cys25Ter) in MLH3 (DNA mismatch repair protein Mlh3) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.89 / 1. The record also includes population frequency data and structural context.
C25* (p.Cys25Ter) variant details
- p.Cys25Ter
- gnomAD rs1310211715
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.887
- CADD 34.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available