G22G (p.Gly22Gly) variant of MLH1 (DNA mismatch repair protein Mlh1)
G22G (p.Gly22Gly) in MLH1 (DNA mismatch repair protein Mlh1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
G22G (p.Gly22Gly) variant details
- p.Gly22Gly
- rs2125694260
- gnomAD 3-36993613-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.244
- CADD 14.80
- Most common in the HGDP:BEDOUIN population (allele frequency 0.012)
- Structural context available
- Literature evidence available