A21A (p.Ala21Ala) variant of MLH1 (DNA mismatch repair protein Mlh1)
A21A (p.Ala21Ala) in MLH1 (DNA mismatch repair protein Mlh1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
A21A (p.Ala21Ala) variant details
- p.Ala21Ala
- rs1553637274
- gnomAD 3-36993610-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.193
- CADD 15.90
- Most common in the Finnish in Finland (FIN) population (allele frequency 5.6e-05)
- Structural context available
- Literature evidence available