E4* (p.Glu4Ter) variant of MITF (O75030)

E4* (p.Glu4Ter) in MITF (O75030) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.

E4* (p.Glu4Ter) variant details