T70I (p.Thr70Ile) variant of MFN2 (Mitofusin-2)
T70I (p.Thr70Ile) in MFN2 (Mitofusin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
T70I (p.Thr70Ile) variant details
- p.Thr70Ile
- Ensembl rs878985218
- Missense
- Variant Prioritization Score for Impact Estimate 0.581
- REVEL 0.49
- CADD 19.30
- PolyPhen-2 0.00
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available