L76M (p.Leu76Met) variant of MFN2 (Mitofusin-2)
L76M (p.Leu76Met) in MFN2 (Mitofusin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
L76M (p.Leu76Met) variant details
- p.Leu76Met
- gnomAD rs1218698482
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.33
- CADD 17.30
- PolyPhen-2 0.33
- SIFT 0.10
- Most common in the Middle Eastern population (allele frequency 0.0011)
- Structural context available