K15E (p.Lys15Glu) variant of MFN2 (Mitofusin-2)
K15E (p.Lys15Glu) in MFN2 (Mitofusin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
K15E (p.Lys15Glu) variant details
- p.Lys15Glu
- ExAC rs778984789
- gnomAD rs778984789
- Missense
- Variant Prioritization Score for Impact Estimate 0.652
- REVEL 0.67
- CADD 25.10
- PolyPhen-2 0.98
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available