Y59H (p.Tyr59His) variant of MERTK (Tyrosine-protein kinase Mer)
Y59H (p.Tyr59His) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
Y59H (p.Tyr59His) variant details
- p.Tyr59His
- ExAC rs748161559
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.16
- MetaLR 0.16
- MetaSVM -0.91
- CADD 3.81
- PolyPhen-2 0.14
- SIFT 0.57
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available