W18R (p.Trp18Arg) variant of MERTK (Tyrosine-protein kinase Mer)
W18R (p.Trp18Arg) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
W18R (p.Trp18Arg) variant details
- p.Trp18Arg
- gnomAD rs1683974540
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- REVEL 0.14
- MetaLR 0.20
- MetaSVM -0.92
- CADD 1.75
- PolyPhen-2 0.00
- SIFT 0.16
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available