W18L (p.Trp18Leu) variant of MERTK (Tyrosine-protein kinase Mer)
W18L (p.Trp18Leu) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
W18L (p.Trp18Leu) variant details
- p.Trp18Leu
- gnomAD 2-111898788-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.262
- REVEL 0.17
- MetaLR 0.19
- MetaSVM -0.91
- CADD 14.20
- PolyPhen-2 0.00
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available