T23N (p.Thr23Asn) variant of MERTK (Tyrosine-protein kinase Mer)
T23N (p.Thr23Asn) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
T23N (p.Thr23Asn) variant details
- p.Thr23Asn
- ExAC rs781350196
- TOPMed rs781350196
- gnomAD rs781350196
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.08
- MetaLR 0.20
- MetaSVM -0.88
- CADD 13.70
- PolyPhen-2 0.06
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available