T23I (p.Thr23Ile) variant of MERTK (Tyrosine-protein kinase Mer)
T23I (p.Thr23Ile) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
T23I (p.Thr23Ile) variant details
- p.Thr23Ile
- ExAC rs781350196
- TOPMed rs781350196
- gnomAD rs781350196
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.10
- MetaLR 0.20
- MetaSVM -0.88
- CADD 15.00
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available