S52T (p.Ser52Thr) variant of MERTK (Tyrosine-protein kinase Mer)
S52T (p.Ser52Thr) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
S52T (p.Ser52Thr) variant details
- p.Ser52Thr
- gnomAD 2-111929212-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.08
- MetaLR 0.22
- MetaSVM -0.95
- CADD 14.20
- PolyPhen-2 0.00
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available