P7T (p.Pro7Thr) variant of MERTK (Tyrosine-protein kinase Mer)
P7T (p.Pro7Thr) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
P7T (p.Pro7Thr) variant details
- p.Pro7Thr
- gnomAD rs1683973586
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.10
- MetaLR 0.16
- MetaSVM -0.98
- CADD 11.40
- PolyPhen-2 0.01
- SIFT 0.74
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available