P7S (p.Pro7Ser) variant of MERTK (Tyrosine-protein kinase Mer)
P7S (p.Pro7Ser) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
P7S (p.Pro7Ser) variant details
- p.Pro7Ser
- gnomAD 2-111898754-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.18
- REVEL 0.11
- MetaLR 0.16
- MetaSVM -0.99
- CADD 12.50
- PolyPhen-2 0.00
- SIFT 0.79
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available