P5S (p.Pro5Ser) variant of MERTK (Tyrosine-protein kinase Mer)
P5S (p.Pro5Ser) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
P5S (p.Pro5Ser) variant details
- p.Pro5Ser
- gnomAD rs1286101631
- Missense
- Variant Prioritization Score for Impact Estimate 0.124
- REVEL 0.07
- MetaLR 0.17
- MetaSVM -0.99
- CADD 9.54
- PolyPhen-2 0.01
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available