P3L (p.Pro3Leu) variant of MERTK (Tyrosine-protein kinase Mer)
P3L (p.Pro3Leu) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
P3L (p.Pro3Leu) variant details
- p.Pro3Leu
- gnomAD 2-111898743-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- REVEL 0.12
- MetaLR 0.15
- MetaSVM -1.00
- CADD 5.24
- PolyPhen-2 0.00
- SIFT 0.72
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available