L8M (p.Leu8Met) variant of MERTK (Tyrosine-protein kinase Mer)
L8M (p.Leu8Met) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
L8M (p.Leu8Met) variant details
- p.Leu8Met
- gnomAD 2-111898757-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.183
- REVEL 0.08
- MetaLR 0.20
- MetaSVM -0.91
- CADD 15.30
- PolyPhen-2 0.15
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available