L6P (p.Leu6Pro) variant of MERTK (Tyrosine-protein kinase Mer)
L6P (p.Leu6Pro) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
L6P (p.Leu6Pro) variant details
- p.Leu6Pro
- gnomAD 2-111898752-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.16
- MetaLR 0.22
- MetaSVM -0.91
- CADD 22.60
- PolyPhen-2 0.01
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available