L17I (p.Leu17Ile) variant of MERTK (Tyrosine-protein kinase Mer)
L17I (p.Leu17Ile) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
L17I (p.Leu17Ile) variant details
- p.Leu17Ile
- gnomAD 2-111898784-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.149
- REVEL 0.07
- MetaLR 0.18
- MetaSVM -0.96
- CADD 2.03
- PolyPhen-2 0.02
- SIFT 0.23
- Population evidence available
- Structural context available
- Literature evidence available