L14V (p.Leu14Val) variant of MERTK (Tyrosine-protein kinase Mer)
L14V (p.Leu14Val) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
L14V (p.Leu14Val) variant details
- p.Leu14Val
- gnomAD 2-111898775-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.09
- MetaLR 0.20
- MetaSVM -0.94
- CADD 9.32
- PolyPhen-2 0.00
- SIFT 0.41
- Population evidence available
- Structural context available
- Literature evidence available