L14I (p.Leu14Ile) variant of MERTK (Tyrosine-protein kinase Mer)
L14I (p.Leu14Ile) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
L14I (p.Leu14Ile) variant details
- p.Leu14Ile
- gnomAD 2-111898775-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.18
- REVEL 0.07
- MetaLR 0.20
- MetaSVM -0.93
- CADD 10.50
- PolyPhen-2 0.03
- SIFT 0.52
- Population evidence available
- Structural context available
- Literature evidence available