L12P (p.Leu12Pro) variant of MERTK (Tyrosine-protein kinase Mer)
L12P (p.Leu12Pro) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
L12P (p.Leu12Pro) variant details
- p.Leu12Pro
- gnomAD 2-111898770-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.498
- REVEL 0.53
- MetaLR 0.23
- MetaSVM -0.89
- CADD 22.90
- PolyPhen-2 0.38
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available