L12I (p.Leu12Ile) variant of MERTK (Tyrosine-protein kinase Mer)
L12I (p.Leu12Ile) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
L12I (p.Leu12Ile) variant details
- p.Leu12Ile
- gnomAD 2-111898769-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.17
- REVEL 0.07
- MetaLR 0.18
- MetaSVM -0.99
- CADD 7.95
- PolyPhen-2 0.02
- SIFT 0.22
- Population evidence available
- Structural context available
- Literature evidence available