L10M (p.Leu10Met) variant of MERTK (Tyrosine-protein kinase Mer)
L10M (p.Leu10Met) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
L10M (p.Leu10Met) variant details
- p.Leu10Met
- gnomAD 2-111898763-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.22
- REVEL 0.10
- MetaLR 0.20
- MetaSVM -0.92
- CADD 22.80
- PolyPhen-2 0.28
- SIFT 0.21
- Population evidence available
- Structural context available
- Literature evidence available