I22V (p.Ile22Val) variant of MERTK (Tyrosine-protein kinase Mer)
I22V (p.Ile22Val) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
I22V (p.Ile22Val) variant details
- p.Ile22Val
- gnomAD 2-111929122-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.109
- REVEL 0.10
- MetaLR 0.10
- MetaSVM -0.94
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.54
- Population evidence available
- Structural context available
- Literature evidence available