G58R (p.Gly58Arg) variant of MERTK (Tyrosine-protein kinase Mer)
G58R (p.Gly58Arg) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
G58R (p.Gly58Arg) variant details
- p.Gly58Arg
- gnomAD rs1423887739
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.12
- MetaLR 0.18
- MetaSVM -0.98
- CADD 17.60
- PolyPhen-2 0.01
- SIFT 0.08
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available