G37A (p.Gly37Ala) variant of MERTK (Tyrosine-protein kinase Mer)
G37A (p.Gly37Ala) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
G37A (p.Gly37Ala) variant details
- p.Gly37Ala
- gnomAD 2-111929168-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.135
- REVEL 0.06
- MetaLR 0.26
- MetaSVM -0.83
- CADD 2.23
- PolyPhen-2 0.10
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available