G11A (p.Gly11Ala) variant of MERTK (Tyrosine-protein kinase Mer)
G11A (p.Gly11Ala) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
G11A (p.Gly11Ala) variant details
- p.Gly11Ala
- Ensembl rs1573554218
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.12
- MetaLR 0.19
- MetaSVM -0.95
- CADD 21.40
- PolyPhen-2 0.17
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available