F13L (p.Phe13Leu) variant of MERTK (Tyrosine-protein kinase Mer)
F13L (p.Phe13Leu) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
F13L (p.Phe13Leu) variant details
- p.Phe13Leu
- gnomAD 2-111898774-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.07
- MetaLR 0.09
- MetaSVM -0.99
- CADD 12.30
- PolyPhen-2 0.00
- SIFT 0.56
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available