A4S (p.Ala4Ser) variant of MERTK (Tyrosine-protein kinase Mer)
A4S (p.Ala4Ser) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
A4S (p.Ala4Ser) variant details
- p.Ala4Ser
- gnomAD rs1326403828
- Missense
- Variant Prioritization Score for Impact Estimate 0.197
- REVEL 0.09
- AlphaMissense 0.16
- MetaLR 0.17
- MetaSVM -0.98
- CADD 15.40
- PolyPhen-2 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available