A29S (p.Ala29Ser) variant of MERTK (Tyrosine-protein kinase Mer)
A29S (p.Ala29Ser) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
A29S (p.Ala29Ser) variant details
- p.Ala29Ser
- gnomAD 2-111929143-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0916
- REVEL 0.05
- MetaLR 0.18
- MetaSVM -0.98
- CADD 1.92
- PolyPhen-2 0.00
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available