A21S (p.Ala21Ser) variant of MERTK (Tyrosine-protein kinase Mer)
A21S (p.Ala21Ser) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
A21S (p.Ala21Ser) variant details
- p.Ala21Ser
- gnomAD 2-111898796-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.20
- MetaLR 0.22
- MetaSVM -0.92
- CADD 24.30
- PolyPhen-2 0.00
- SIFT 0.21
- Population evidence available
- Structural context available
- Literature evidence available