A16T (p.Ala16Thr) variant of MERTK (Tyrosine-protein kinase Mer)
A16T (p.Ala16Thr) in MERTK (Tyrosine-protein kinase Mer) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
A16T (p.Ala16Thr) variant details
- p.Ala16Thr
- cosmic curated COSV10882
- ExAC rs756874549
- gnomAD rs756874549
- Missense
- Variant Prioritization Score for Impact Estimate 0.259
- REVEL 0.10
- MetaLR 0.21
- MetaSVM -0.90
- CADD 19.70
- PolyPhen-2 0.01
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available