I91T (p.Ile91Thr) variant of MEFV (Pyrin)
I91T (p.Ile91Thr) in MEFV (Pyrin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
I91T (p.Ile91Thr) variant details
- p.Ile91Thr
- Ensembl rs1959114123
- Missense
- Variant Prioritization Score for Impact Estimate 0.131
- REVEL 0.14
- CADD 1.65
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available