T2T (p.Thr2Thr) variant of MDM4 (Protein Mdm4)
T2T (p.Thr2Thr) in MDM4 (Protein Mdm4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
T2T (p.Thr2Thr) variant details
- p.Thr2Thr
- rs758733517
- gnomAD 1-204525524-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.138
- CADD 8.12
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score -0.161
- Literature evidence available