T2A (p.Thr2Ala) variant of MDM4 (Protein Mdm4)
T2A (p.Thr2Ala) in MDM4 (Protein Mdm4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, experimental measurements, and structural context.
T2A (p.Thr2Ala) variant details
- p.Thr2Ala
- TOPMed rs1382884218
- gnomAD rs1382884218
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.05
- CADD 19.40
- PolyPhen-2 0.00
- SIFT 0.06
- Population evidence available
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score -0.161