T12T (p.Thr12Thr) variant of MDM4 (Protein Mdm4)
T12T (p.Thr12Thr) in MDM4 (Protein Mdm4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
T12T (p.Thr12Thr) variant details
- p.Thr12Thr
- gnomAD 1-204525554-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.136
- CADD 7.82
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score -0.373
- Literature evidence available