S3S (p.Ser3Ser) variant of MDM4 (Protein Mdm4)

Name: MDM4 S3S (p.Ser3Ser) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-22
License: https://catvariant.com/terms-of-use

S3S (p.Ser3Ser) in MDM4 (Protein Mdm4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.

S3S (p.Ser3Ser) variant details

p.Ser3Ser
rs764353353
gnomAD 1-204525527-A-G
Synonymous
Variant Prioritization Score for Impact Estimate 0.144
CADD 8.90
Most common in the Non-Finnish European population (allele frequency 1.8e-06)
Structural context available
MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score -0.259
Literature evidence available