S15G (p.Ser15Gly) variant of MDM4 (Protein Mdm4)
S15G (p.Ser15Gly) in MDM4 (Protein Mdm4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S15G (p.Ser15Gly) variant details
- p.Ser15Gly
- gnomAD 1-204525561-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.133
- REVEL 0.04
- CADD 19.50
- PolyPhen-2 0.06
- SIFT 0.05
- Population evidence available
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score -0.215
- Literature evidence available