S11S (p.Ser11Ser) variant of MDM4 (Protein Mdm4)
S11S (p.Ser11Ser) in MDM4 (Protein Mdm4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S11S (p.Ser11Ser) variant details
- p.Ser11Ser
- gnomAD 1-204525551-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.425
- CADD 10.90
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score -1.24
- Literature evidence available