Q9E (p.Gln9Glu) variant of MDM4 (Protein Mdm4)
Q9E (p.Gln9Glu) in MDM4 (Protein Mdm4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, experimental measurements, and structural context.
Q9E (p.Gln9Glu) variant details
- p.Gln9Glu
- gnomAD rs1202317431
- Missense
- Variant Prioritization Score for Impact Estimate 0.28
- REVEL 0.03
- CADD 22.60
- PolyPhen-2 0.04
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score -0.144