Q23P (p.Gln23Pro) variant of MDM4 (Protein Mdm4)
Q23P (p.Gln23Pro) in MDM4 (Protein Mdm4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, experimental measurements, and structural context.
Q23P (p.Gln23Pro) variant details
- p.Gln23Pro
- ESP rs369657471
- ExAC rs369657471
- TOPMed rs369657471
- gnomAD rs369657471
- Missense
- Variant Prioritization Score for Impact Estimate 0.323
- REVEL 0.07
- CADD 20.70
- PolyPhen-2 0.09
- SIFT 0.10
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score 0.0188