Q23K (p.Gln23Lys) variant of MDM4 (Protein Mdm4)
Q23K (p.Gln23Lys) in MDM4 (Protein Mdm4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, experimental measurements, and structural context.
Q23K (p.Gln23Lys) variant details
- p.Gln23Lys
- gnomAD rs1428358052
- Missense
- Variant Prioritization Score for Impact Estimate 0.23
- REVEL 0.03
- CADD 21.50
- PolyPhen-2 0.01
- SIFT 0.04
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score 0.0188