Q23H (p.Gln23His) variant of MDM4 (Protein Mdm4)
Q23H (p.Gln23His) in MDM4 (Protein Mdm4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, experimental measurements, and structural context.
Q23H (p.Gln23His) variant details
- p.Gln23His
- ExAC rs773983041
- gnomAD rs773983041
- Missense
- Variant Prioritization Score for Impact Estimate 0.107
- REVEL 0.05
- CADD 17.90
- PolyPhen-2 0.00
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score 0.0188