P21P (p.Pro21Pro) variant of MDM4 (Protein Mdm4)
P21P (p.Pro21Pro) in MDM4 (Protein Mdm4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P21P (p.Pro21Pro) variant details
- p.Pro21Pro
- gnomAD 1-204525581-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.145
- CADD 9.13
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score -0.285
- Literature evidence available