N25I (p.Asn25Ile) variant of MDM4 (Protein Mdm4)
N25I (p.Asn25Ile) in MDM4 (Protein Mdm4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, experimental measurements, and structural context.
N25I (p.Asn25Ile) variant details
- p.Asn25Ile
- gnomAD rs1011975434
- Missense
- Variant Prioritization Score for Impact Estimate 0.0941
- REVEL 0.03
- CADD 17.50
- PolyPhen-2 0.08
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score -1