I24V (p.Ile24Val) variant of MDM4 (Protein Mdm4)
I24V (p.Ile24Val) in MDM4 (Protein Mdm4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, experimental measurements, and structural context.
I24V (p.Ile24Val) variant details
- p.Ile24Val
- gnomAD rs1345762411
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.06
- CADD 13.50
- PolyPhen-2 0.00
- SIFT 0.20
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score 0.103