I24T (p.Ile24Thr) variant of MDM4 (Protein Mdm4)
I24T (p.Ile24Thr) in MDM4 (Protein Mdm4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
I24T (p.Ile24Thr) variant details
- p.Ile24Thr
- gnomAD 1-204525589-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.183
- REVEL 0.02
- CADD 12.30
- PolyPhen-2 0.00
- SIFT 0.47
- Population evidence available
- Structural context available
- MDM4 Zinc finger, RanBP2-type domain domainome 1.0: score 0.103
- Literature evidence available